American Society of Microbiology ABMM Prüfungsthemen:
| Abschnitt | Ziele |
|---|---|
| Thema 1: Grundlagen von Infektionskrankheiten | - Epidemiologie
|
| Thema 2: Klinische Mikrobiologie | - Virologie
|
| Thema 3: Labormanagement und Qualitätssicherungssysteme | - Qualitätssicherung und Qualitätskontrolle
|
| Thema 4: Labordurchführung und Betriebsabläufe | - Diagnostischer Ablauf
|
American Society of Microbiology ABMM ABMM Prüfungsfragen mit Lösungen
Microscopic examination of a potassium hydroxide (KOH) preparation of skin scrapings from a patient with tinea versicolor typically reveals:
- A. Cigar-shaped yeast cells
- B. Septate hyphae and arthroconidia
- C. Short, unbranched hyphae and globose yeast cells in clusters ("spaghetti and meatballs")
- D. Broad, aseptate hyphae with sporangiophores
Antwort: C 🗳️
Acyclovir is a commonly used antiviral agent effective against Herpes Simplex Virus (HSV) and Varicella- Zoster Virus (VZV). Its selective toxicity relies on which initial step for activation within infected cells?
- A. Phosphorylation by host cell mitochondrial kinases
- B. Direct inhibition of viral RNA polymerase activity
- C. Blocking viral entry through competitive inhibition of cellular receptors
- D. Monophosphorylation primarily by viral thymidine kinase
Antwort: D 🗳️
A patient presents with symptoms suggestive of primary syphilis. Which diagnostic test typically becomes positive earliest in the course of infection?
- A. Darkfield microscopy of lesion exudate
- B. Venereal Disease Research Laboratory (VDRL) test on CSF
- C. Treponema pallidum particle agglutination (TP-PA)
- D. Rapid Plasma Reagin (RPR)
Antwort: A 🗳️
A Gram-positive rod is isolated from the blood culture of a neonate with sepsis. The organism exhibits weak beta-hemolysis on sheep blood agar, is catalase-positive, hydrolyzes esculin in the presence of bile, and demonstrates characteristic "tumbling" motility in a wet mount prepared from a broth culture incubated at 25°C. Which organism is most likely?
- A. Corynebacterium jeikeium
- B. Bacillus anthracis
- C. Listeria monocytogenes
- D. Erysipelothrix rhusiopathiae
Antwort: C 🗳️
A research laboratory is investigating the development of a broadly protective vaccine against coronaviruses.
They are focusing on conserved epitopes in the spike (S) protein that are accessible to neutralizing antibodies across different beta-coronaviruses. Which region of the S protein is considered a promising target for such a vaccine?
- A. The S1 subunit, which is primarily responsible for host cell receptor binding.
- B. The S2 subunit, which is more conserved and mediates membrane fusion.
- C. The receptor-binding domain (RBD), which exhibits high sequence variability.
- D. The N-terminal domain (NTD) of the S protein.
Antwort: B 🗳️
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